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Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1633364437298-QC206XD9IDRZD5IB5JMT/30SEP21_HeysLab_Icons-04-scaled-125.png Research - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/83da2c8b-8c6e-4d4a-9bf4-316c36a28d8f/18NOV21_HeysLab_Illustrations_01.png Research Chronic deep brain imaging via microprism. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/532a370f-e22c-40f6-a03e-c8cb673acad9/18NOV21_HeysLab_Illustrations_02.png Research Imaging methods allow for chronic sub-cellular resolution imaging. Image on top shows sparse labelling technique designed to monitor calcium dynamics across the dendritic arbor and at individual synaptic spines during memory-guided behavior. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/0db87b40-c639-48f0-a5ce-a8650c3f1a62/Sparse+GCaMP+Imaging+Single+Plane.gif Research Sparse GCaMP expression in MEC. Left, average DF/F image. Right, DF/F time series collected during virtual navigation. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/3b8c6546-d261-4da1-a13a-da45638c5fbf/18NOV21_HeysLab_Illustrations_03.png Research Mice learn to perform head-fixed virtual navigation tasks designed to probe spatial and temporal memory. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/f4822a2c-7d3a-415f-af71-09443377bfea/IMG_2259.jpg Research Virtual Doorstop timing task: Mice learn to run down and stop at an invisible door for particular wait intervals (eg. 6 or 8 seconds). https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/815851d6-d4cc-494c-847b-cf8648b7f778/Slide7.png Research Regular sequential neural activation during doorstop timing period. Heatmap (right) shows timing fields spread over the entire wait time period. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/71074629-f5a4-489f-96ea-be1466d0ce28/Cells+Heat+MapV1.jpg Research Updated imaging methods allow us to do large-scale multi-plane recordings from hundreds up to thousands of simultaneously recorded neurons in deep brain structures like MEC. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/20bbda40-24cc-49a9-acce-eb69145ca576/Picture9.png Research Multi-plane imaging allows for large scale population recording from the same or across neighboring cortical layers. https://www.heyslab.org/home daily 1.0 2025-11-20 https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1634156722966-ZWCI91PSPZA5PKU44EBQ/Heys+Lab+Animation+OCT+21+R4+%281%29.gif Home - Our Approach Our lab uses a combination of in vivo 2-photon microscopy, high-throughput single-unit electrophysiology and sophisticated behavioral approaches - such as virtual reality - in order to monitor and manipulate neural activity at cellular and sub-cellular resolution in behaving rodents. By combining these experimental approaches with computational modeling, we aim to elucidate the neural mechanisms that underlie encoding, storage and retrieval of spatial and temporal memories. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1631451105960-KMV5218IGZILEI0K0SP1/Heys-01.png Home - Mentorship & Environment The Heys Lab is committed to providing thoughtful mentorship and a balanced work-life environment, with the goal of supporting trainees while they launch successful scientific careers. https://www.heyslab.org/philosophy daily 0.75 2021-09-30 https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632275499968-R731WP8R36I96HNVBJ6P/autumn-aerials.jpg Philosophy - In the Heys Lab we're striving to build a diverse community of critical thinkers that are collaborative, compassionate, and honest. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632175604417-P34KJD6YHBAW66PM8CVY/hike_heys_circle.png Philosophy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632175691745-33A1SM3PR1A06E7SRNW5/coffee_heys_circle.png Philosophy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632176091592-EOM8XJM2SZOXNBANR5WH/imageedit_65_9498350797.png Philosophy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632175919292-6ZE89X3RUR8QJ0H4DT02/solitude_heys_circle.png Philosophy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.heyslab.org/funding daily 0.75 2023-06-27 https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632151056679-C6I5R2IR7FA9363QEO23/HRHR+NIA+final+graphic.jpeg Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/9c3bb8e7-2e64-4d9f-962f-e29eadceabb1/NSF_Official_logo_High_Res_1200ppi.png Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/aad39dd1-c296-467b-b432-a00014f8bfb7/NIH-NIMH-logo-new.png Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632151533740-DLI0FM8EHCUGXNEY67A9/Brain_Behavior_Research_Foundation_logo.png Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/613cc0f34d65b107fd2e20ad/1632152019731-OPWRSJJPBP05SQXH9F8G/whitehall_logo.gif Funding - Make it stand out Whatever it is, the way you tell your story online can make all the difference.